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Sitagliptin 50mg + Metformin 500mg Tablets

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Description

Sitagliptin 50 mg + Metformin 500 mg Tablets – Product Description

Sitagliptin 50 mg + Metformin 500 mg Tablets are a combination anti-diabetic medication used for the effective management of Type 2 Diabetes Mellitus. This dual-action formulation combines Sitagliptin, a DPP-4 inhibitor, and Metformin, a biguanide, to help control blood sugar levels more effectively when diet and exercise alone are not sufficient.

Composition

Each film-coated tablet contains:

  • Sitagliptin – 50 mg

  • Metformin Hydrochloride – 500 mg

  • Excipients – q.s.

Therapeutic Class

  • Anti-Diabetic Medicine

  • DPP-4 Inhibitor + Biguanide Combination

Indications / Uses

This combination is indicated for:

  • Management of Type 2 Diabetes Mellitus

  • Improving glycemic control in adults

  • Patients who require combination therapy for better blood sugar control

  • Can be used along with diet, exercise, and lifestyle changes

Mechanism of Action

This medicine works through two complementary mechanisms:

Sitagliptin

  • Inhibits the DPP-4 enzyme

  • Increases incretin hormone levels

  • Enhances insulin release after meals and reduces glucagon levels

Metformin

  • Reduces glucose production in the liver

  • Improves insulin sensitivity

  • Helps the body utilize insulin more effectively

Key Benefits

  • Provides better blood glucose control through dual action

  • Helps reduce fasting and post-meal blood sugar levels

  • Improves insulin function in the body

  • Supports long-term diabetes management

Dosage & Administration

  • Usually taken once or twice daily with meals as directed by a healthcare professional

  • Tablets should be swallowed whole with water

Possible Side Effects

Some patients may experience mild side effects such as:

  • Nausea

  • Diarrhea

  • Stomach upset

  • Headache

  • Low blood sugar (when combined with other anti-diabetic medicines)

Storage Instructions

  • Store in a cool and dry place below 25°C

  • Protect from moisture and direct sunlight

  • Keep out of reach of children

⚠️ Note: This medication should be taken only under the supervision of a qualified healthcare professional.

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