Description
Sitagliptin 100 mg + Dapagliflozin 10 mg Tablets
Sitagliptin 100 mg + Dapagliflozin 10 mg Tablets are a combination anti-diabetic medication used for the effective management of Type 2 Diabetes Mellitus. This advanced formulation combines Sitagliptin, a DPP-4 inhibitor, and Dapagliflozin, an SGLT-2 inhibitor, to help control blood sugar levels through complementary mechanisms.
Composition
Each film-coated tablet contains:
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Sitagliptin – 100 mg
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Dapagliflozin – 10 mg
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Excipients – q.s.
Therapeutic Class
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Anti-Diabetic Medicine
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DPP-4 Inhibitor + SGLT-2 Inhibitor Combination
Indications / Uses
This combination is indicated for:
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Management of Type 2 Diabetes Mellitus
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Improving glycemic control in adults when diet and exercise alone are not sufficient
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Patients requiring dual therapy for better blood sugar control
Mechanism of Action
Sitagliptin
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Inhibits the DPP-4 enzyme
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Increases incretin hormone levels
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Enhances insulin secretion and reduces glucagon levels after meals
Dapagliflozin
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Inhibits SGLT-2 (Sodium-Glucose Cotransporter-2) in the kidneys
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Reduces glucose reabsorption
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Helps remove excess glucose through urine
Key Benefits
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Provides dual mechanism blood sugar control
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Helps reduce fasting and post-meal glucose levels
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Supports better insulin response
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Helps in long-term diabetes management
Dosage & Administration
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Typically taken once daily or as directed by a healthcare professional
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The tablet may be taken with or without food
Possible Side Effects
Some patients may experience mild side effects such as:
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Frequent urination
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Urinary tract infection
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Headache
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Nausea
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Low blood sugar (especially when used with other anti-diabetic medicines)
Storage Instructions
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Store in a cool and dry place below 25°C
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Protect from moisture and sunlight
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Keep out of reach of children
⚠️ Note: This medication should be used only under the supervision of a qualified healthcare professional.






